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Mol Divers. 2009 Nov;13(4):545-9. doi: 10.1007/s11030-009-9132-1. Epub 2009 Mar 20.

An efficient protocol for the synthesis of 2-amino-4,6-diphenylpyridine-3-carbonitrile using ionic liquid ethylammonium nitrate.

Author information

1
Department of Chemistry, JES College, Jalna, 431203, MS, India.

Abstract

Chalcones on condensation with malononitrile and ammonium acetate in the presence of ionic liquid ethylammonium nitrate affords the corresponding 2-amino-4, 6-diphenylpyridine-3-carbonitrile in excellent yield. The ionic liquid is recycled and reused several times.

PMID:
19301139
DOI:
10.1007/s11030-009-9132-1
[Indexed for MEDLINE]

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