Format

Send to

Choose Destination
See comment in PubMed Commons below
Int J Radiat Biol. 2009 Mar;85(3):196-213. doi: 10.1080/09553000902748575.

Genetic damage in mammalian somatic cells exposed to extremely low frequency electro-magnetic fields: a meta-analysis of data from 87 publications (1990-2007).

Author information

  • 1Department of Radiation Oncology, University of Texas Health Sciences Center, San Antonio, TX 78229, USA. vijay@uthscsa.edu

Abstract

PURPOSE:

A meta-analysis was conducted to obtain a 'quantitative' estimate of the extent of genetic damage in mammalian somatic cells exposed to non-ionizing radiation emitted from extremely low frequency electro-magnetic fields (ELF-EMF) and to compare with that in unexposed control cells.

METHODS:

The methods used for the meta-analysis were recommended in several standard text books. Three specific variables related to ELF-EMF exposure characteristics were examined in the meta-analysis: (i) frequency (Hz), (ii) flux density (mT), and (iii) in occupationally exposed individuals.

RESULT AND CONCLUSIONS:

(1) The difference between ELF-EMF-exposed and control cells as well as the 'effect size' due to ELF-EMF exposure were biologically small (although statistically significant) with very few exceptions. (2) At certain ELF-EMF exposure conditions there was a statistically significant increase in genetic damage assessed from some end-points. (3) The mean indices for chromosomal aberrations and micronuclei end-points in ELF-EMF-exposed and control cells were within the spontaneous levels reported in historical database. (4) Considerable evidence for publication bias was found in the meta-analysis.

PMID:
19296340
DOI:
10.1080/09553000902748575
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis
    Loading ...
    Support Center