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Chembiochem. 2009 Apr 17;10(6):974-6. doi: 10.1002/cbic.200800824.

A mechanism for stochastic decision making by bacteria.

Author information

1
Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Abstract

What mechanism underlies the induction of the lac operon? Expression from the lac operon is an all-or-none phenomenon. Recent work by Choi et al. combines single-molecule imaging of gene expression with single-cell induction measurements to develop a stochastic model describing the critical role of single lac-repressor molecules in induction.

PMID:
19294726
DOI:
10.1002/cbic.200800824
[Indexed for MEDLINE]

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