Format

Send to

Choose Destination
Angew Chem Int Ed Engl. 2009;48(16):2941-5. doi: 10.1002/anie.200805996.

Total synthesis of ciguatoxin.

Author information

1
Laboratory of Organic Chemistry, Bioagricultural Sciences, Nagoya University, Furocho, Chikusa 464-8601, Nagoya, Japan.

Abstract

Something fishy: Ciguatoxin (see structure) is one of the principal toxins involved in ciguatera poisoning and the target of a total synthesis involving the coupling of three segments. The key transformations in this synthesis feature acetylene-dicobalthexacarbonyl complexation.

PMID:
19294712
DOI:
10.1002/anie.200805996
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center