Format

Send to

Choose Destination
Environ Toxicol Chem. 2009 Aug;28(8):1783-5. doi: 10.1897/08-563.1.

Reversibility of estrogenic sex changes in zebrafish (Danio rerio).

Author information

1
Department of Biological Sciences, Zoophysiology, C.F. Moellers Allé 3, University of Aarhus, Building 1131, DK-8000 Aarhus C, Denmark.

Abstract

Development of male zebrafish (Danio rerio) courtship behavior was studied following estrogenic disruption of sexual differentiation. Sixty zebrafish were exposed at 28 degrees C to 5 ng/L (nominal concentration) of 17alpha-ethinylestradiol (EE2) from the egg stage until adulthood at four months of age, resulting in a female-biased sex ratio. Twenty-five EE2-exposed phenotypic female zebrafish were subsequently held in clean water for eight months. During this period, eight phenotypic males developed. These phenotypic males demonstrated significant behavioral aberrations and a low fertilization rate compared to control males.

PMID:
19290683
DOI:
10.1897/08-563.1
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center