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Ann Emerg Med. 1991 Oct;20(10):1121-4.

Bone marrow aspirate as an accessible and reliable source for critical laboratory studies.

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1
Department of Emergency Medicine, Children's Hospital, Oakland, California 94609.

Abstract

STUDY OBJECTIVE:

To determine whether laboratory studies performed on bone marrow aspirate can be used to predict values in the peripheral blood of human beings.

DESIGN:

Prospective correlative study.

SETTING:

Tertiary care pediatric hospital.

TYPE OF PARTICIPANTS:

Fifteen patients from the hematology-oncology division of Children's Hospital, Oakland, California, were studied during routine diagnostic bone marrow aspirations.

INTERVENTIONS:

Aliquots of serum and bone marrow obtained as part of routine diagnostic studies were analyzed.

MEASUREMENTS AND MAIN RESULTS:

Venous and bone marrow samples were analyzed for blood gas values, hemoglobin, and serum chemistries. Bone marrow specimens were found to reliably predict venous values of pH, bicarbonate, base excess, PCO2, hematocrit, sodium, chloride, and glucose. Bone marrow was not predictive of blood oxygenation, potassium, or ionized calcium.

CONCLUSION:

This study demonstrates in human beings what has previously been shown in animals--that the bone marrow is an alternative source of blood for a variety of laboratory studies.

PMID:
1928886
[Indexed for MEDLINE]

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