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Support Care Cancer. 2009 Jun;17(6):753-5. doi: 10.1007/s00520-009-0608-4. Epub 2009 Mar 11.

Radiological imaging change in a malignant bowel obstruction patient treated with octreotide.

Author information

1
Palliative Care Unit, Shakaihoken Kobe Central Hospital, 2-1-1 Souyama-cho, Kita-ku, Kobe, Hyogo 651-1145, Japan. shinjo@doctor.email.ne.jp

Abstract

INTRODUCTION:

Malignant bowel obstruction (MBO) is a complication in advanced cancer patients with abdominal and pelvic malignancy. Recent research has established the efficacy of octreotide for MBO-related symptom relief. The mechanism that octreotide increases water absorption in case of MBO has not been demonstrated except for experimental animal and normal human model.

CASE REPORT:

We present a 60-year-old man with pancreatic cancer and MBO treated with octreotide. Radiological imaging showed the disappearance of large-volume fluid retention in the small intestine with alleviating vomiting within 2 days. This radiological change might result from the effect of octreotide increasing water absorption in intestine tract.

PMID:
19277723
DOI:
10.1007/s00520-009-0608-4
[Indexed for MEDLINE]

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