[Investigation of triazavirin antiviral activity against influenza A virus (H5N1) in cell culture]

Antibiot Khimioter. 2007;52(11-12):18-20.
[Article in Russian]

Abstract

Analysis of triazavirin efficacy with respect to influenza A virus (H5N1) in sensitive cell culture MDSK vs. effective antigrippe drugs, such as tamiflu, remantadin and arbidol showed that triazavirin in a wide range of the concentrations was efficient in inhibition of the virus cytopathic activity and formation of the specific hemagglutinin.

MeSH terms

  • Animals
  • Antiviral Agents / pharmacology*
  • Azoles / pharmacology*
  • Cell Line
  • Dogs
  • Hemagglutinins, Viral / biosynthesis
  • Influenza A Virus, H5N1 Subtype / drug effects*
  • Triazines / pharmacology*
  • Triazoles

Substances

  • Antiviral Agents
  • Azoles
  • Hemagglutinins, Viral
  • Triazines
  • Triazoles
  • riamilovir