Format

Send to

Choose Destination
See comment in PubMed Commons below
Curr Eye Res. 2009 Mar;34(3):231-7. doi: 10.1080/02713680802710692.

Intravitreal bevacizumab (Avastin) injection in retinitis pigmentosa.

Author information

1
Bilim University, Istanbul, Turkey. erdalyuzbasioglu@mynet.com

Abstract

PURPOSE:

To evaluate and report the effectiveness, visual, anatomical, and clinical outcome of intravitreal bevacizumab (Avastin) injection in patients with retinitis pigmentosa (RP).

METHODS:

Our prospective study included 13 eyes of 7 patients (4 women and 3 men) in the age range of 25-69 years (mean 44.14 years) with cystoid macular edema (CME) secondary to RP. Intravitreal bevacizumab at a dose of 1.25 mg/0.05 ml was injected via a 28-gauge needle. The response rate to treatment was monitored functionally by visual acuity assessment and anatomically using the optical coherence tomography.

RESULTS:

The baseline mean central macular thickness was 370.15 microm (range 245-603 microm. The central macular thickness decreased to 142.53 microm (range 124-168 microm) after bevacizumab injections. The pre- and post-treatment visual acuity ranges were 5/400-20/100 and 20/200-20/63, respectively.

CONCLUSIONS:

Our data reveal that intravitreal bevacizumab administration is effective for the treatment of CME in RP. Further studies with a larger population and longer follow-up period are warranted to assess the efficacy of the treatment.

PMID:
19274531
DOI:
10.1080/02713680802710692
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis
    Loading ...
    Support Center