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Clin Biochem. 2009 Jul;42(10-11):1190-3. doi: 10.1016/j.clinbiochem.2009.02.023. Epub 2009 Mar 6.

Prognostic value of increased adiponectin plasma concentrations in patients with acute destabilized heart failure.

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1
Department of Laboratory Medicine, Konventhospital Barmherzige Brueder, Seilerstaette 2-4, A-4020 Linz, Austria.

Abstract

OBJECTIVES:

To evaluate the prognostic value of adiponectin in patients with acute destabilized heart failure.

DESIGN AND METHODS:

Adiponectin was measured in 137 consecutive heart failure patients attending an emergency department. The endpoint was 1-year all-cause mortality.

RESULTS:

In Cox proportional-hazards regression, an adiponectin plasma concentration>24.1 mg/L had a risk ratio of 2.46 (95% CI, 1.24-4.87), independently of classical risk factors and B-type natriuretic peptide.

CONCLUSIONS:

Adiponectin predicts mortality in patients with acute destabilized heart failure.

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