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Biosci Biotechnol Biochem. 2009 Mar 23;73(3):769-71. Epub 2009 Mar 7.

SK66-his, a novel glycine-rich peptide derived from Drosophila with antibacterial activity.

Author information

1
Key Laboratory of Molecular Biophysics, Ministry of Education, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Abstract

SK(66)-his, a novel glycine-rich peptide derived from the CG13551 gene of Drosophila, was directly expressed in Escherichia coli with the help of the glucose effect of the lac repressor and efficiently purified in high yield (10.063 mg/l). It showed significant activity against Gram-positive bacteria. We determined a MIC value of 9 microg ml(-1) with Bacillus thuringiensis.

PMID:
19270403
DOI:
10.1271/bbb.80756
[Indexed for MEDLINE]
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