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AJNR Am J Neuroradiol. 2009 Apr;30(4):662-8. doi: 10.3174/ajnr.A1487. Epub 2009 Mar 6.

Theoretic basis and technical implementations of CT perfusion in acute ischemic stroke, part 1: Theoretic basis.

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1
Department of Radiology, Massachusetts General Hospital, Boston, Mass. 02114, USA. akonstas@partners.org

Abstract

CT perfusion (CTP) is a functional imaging technique that provides important information about capillary-level hemodynamics of the brain parenchyma and is a natural complement to the strengths of unenhanced CT and CT angiography in the evaluation of acute stroke, vasospasm, and other neurovascular disorders. CTP is critical in determining the extent of irreversibly infarcted brain tissue (infarct "core") and the severely ischemic but potentially salvageable tissue ("penumbra"). This is achieved by generating parametric maps of cerebral blood flow, cerebral blood volume, and mean transit time.

PMID:
19270105
DOI:
10.3174/ajnr.A1487
[Indexed for MEDLINE]
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