Send to

Choose Destination
AJNR Am J Neuroradiol. 2009 Apr;30(4):662-8. doi: 10.3174/ajnr.A1487. Epub 2009 Mar 6.

Theoretic basis and technical implementations of CT perfusion in acute ischemic stroke, part 1: Theoretic basis.

Author information

Department of Radiology, Massachusetts General Hospital, Boston, Mass. 02114, USA.


CT perfusion (CTP) is a functional imaging technique that provides important information about capillary-level hemodynamics of the brain parenchyma and is a natural complement to the strengths of unenhanced CT and CT angiography in the evaluation of acute stroke, vasospasm, and other neurovascular disorders. CTP is critical in determining the extent of irreversibly infarcted brain tissue (infarct "core") and the severely ischemic but potentially salvageable tissue ("penumbra"). This is achieved by generating parametric maps of cerebral blood flow, cerebral blood volume, and mean transit time.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center