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Curr Opin Microbiol. 2009 Apr;12(2):215-20. doi: 10.1016/j.mib.2009.02.001. Epub 2009 Mar 9.

Responses of Pseudomonas to small toxic molecules by a mosaic of domains.

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1
Consejo Superior de Investigaciones Científica, Estación Experimental del Zaidín, Department of Environmental Protection, Granada, Spain. jlramos@eez.csic.es

Abstract

Transcriptional responses of microorganisms to environmental perturbations are broad and complex, and often involve regulatory cascades in which an interplay of regulatory factors trigger a specific expression program. Here, we describe how Pseudomonas responds to challenges from toxic chemicals, for which they use a dedicated program that subsequently confers resistance to these compounds. A mosaic of domains has been recruited to sense and metabolize these chemicals in order to obtain energy and carbon.

PMID:
19269884
DOI:
10.1016/j.mib.2009.02.001
[Indexed for MEDLINE]
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