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Encephale. 2009 Jan;35 Suppl 2:S80-3. doi: 10.1016/S0013-7006(09)75540-X.

[Schizophrenia and circadian rhythms].

[Article in French]

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Hôpital Saint-Jacques, 85, rue Saint-Jacques, 44093 Nantes cedex.


Circadian rhythms have not been widely studied in schizophrenic patients, probably for methodological feasibility reasons. The available findings relate to the awake/asleep cycle and are not particularly up to date. Clinically' the reduction in overall sleep time and sleep fragmentation are usual but relatively non-specific findings in decompensated psychotic episodes. Although H Ey's hypothesis of intermediate sleep by has not been followed up, EEG recordings support moderate abnormalities linked to certain times of progression such as a possible increase in MOR density or reduction in REM latency in delusional phases. The reduction in SLP is thought to be more a marker of the schizophrenic state as an illness. A possible action of some antipsychotics on sleep fragmentation would give them resynchronising activity, which remains to be confirmed.

[Indexed for MEDLINE]

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