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Cell Stem Cell. 2009 Mar 6;4(3):196-7. doi: 10.1016/j.stem.2009.02.008.

A radical bailout strategy for cancer stem cells.

Author information

1
Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA. zuzana_tothova@hms.harvard.edu

Abstract

In a recent issue of Nature, Diehn et al. (2009) demonstrate that breast cancer stem cells (CSCs) maintain lower levels of reactive oxygen species (ROS) than their nontumorigenic counterparts. Their studies provide a link between the management of ROS by CSCs and enhanced tumor radioresistance.

PMID:
19265655
DOI:
10.1016/j.stem.2009.02.008
[Indexed for MEDLINE]
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