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Surg Endosc. 2009 Jun;23(6):1191-7. doi: 10.1007/s00464-009-0373-y. Epub 2009 Mar 5.

Meta-analysis of skin adhesives versus sutures in closure of laparoscopic port-site wounds.

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  • 1Department of Colorectal Surgery, Worthing Hospital, Washington Suite, North Wing, Worthing, West Sussex, BN11 2DH, UK.



To analyze the effectiveness of skin adhesives and sutures in the closure of laparoscopic port-site wounds.


Electronic databases were searched to find relevant randomized controlled trials and their data was analyzed to generate a summative outcome.


Seven trials on port-site wound closure after laparoscopic procedures encompassing 902 patients were retrieved from the electronic databases. Four randomized controlled trials on 404 patients qualified for the review according to inclusion criteria. In both fixed- and random-effects models, there was no difference between the two port-site wound closure techniques in terms of wound infection, wound dehiscence and, patient satisfaction. However, statistically tissue adhesives were quicker in port-site wound closure as compared with sutures.


Based on this review, there is insufficient evidence that port-site wound closure technique by tissue adhesives is superior to traditional suture closure technique in terms of wound infection, wound dehiscence, and patient satisfaction. However, tissue adhesives are quicker in port-site wound closure. A multicentre randomized controlled trial is required in order to obtain stronger evidence.

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