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Toxicon. 1991;29(7):898-900.

Chymotrypsin treatment increases the activity of Clostridium perfringens enterotoxin.

Author information

1
Department of Food Hygiene, Norwegian College of Veterinary Medicine, Oslo.

Abstract

Chymotrypsin treatment of the enterotoxin from Clostridium perfringens results in the loss of 36 amino acids from the N-terminus and 3 amino acids from the C-terminus. This processing results in a 3.2 fold increase in activity on Vero cells, which is close to what had been found for trypsin treatment following the loss of 25 amino acids from the N-terminus.

PMID:
1926189
[Indexed for MEDLINE]

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