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Acta Biomed. 2008 Dec;79(3):205-10.

Clinical efficacy, safety and tolerability of BIO-C (micronized Silymarin) as a galactagogue.

Author information

1
Velleja Research, Pontenure, PC, Italy. f.dipierro@vellejaresearch.com

Abstract

BACKGROUND AND AIM OF THE WORK:

The authors have previously reported the use of Silymarin (a Silybum marianum standardized extract) as a promoter of milk production in cows. Due to the important psychological impact of hypogalactia in women after delivery, we evaluated the role of Silymarin as a safe and effective galactogogue for human species.

METHODS:

50 healthy women during lactation were enrolled in order to verify the galactogogue role played by an oral treatment with micronized Silymarin (420 mg/day) in comparison with an undistinguishable placebo product.

RESULTS:

Women orally treated for 63 days with Silymarin showed a clear galactagogue role for the product with an increase of 85.94% of the daily milk production (placebo: +32.09%). No drop out, nor unwanted effects were reported in both groups. Compliance and tolerability were also very good.

CONCLUSIONS:

Silymarin may be considered as a safe and effective herbal product that can be orally administered in order to improve the daily milk production in healthy women after delivery, without affecting milk quality.

PMID:
19260380
[Indexed for MEDLINE]

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