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Zhongguo Zhong Yao Za Zhi. 2008 Dec;33(23):2764-7.

[Study of determination method for heavy metals and harmful elements residues in four traditional Chinese medicine injections].

[Article in Chinese]

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  • 1National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China.


Methods for determination of heavy metals and harmful residues in traditional Chinese medicine injection were established. Graphite furnace atomic absorption spectrometry was used for determination of lead, cadmium and copper, atomic fluorescence spectrometry for arsenic and mercury. The preprocessing method was optimized. The average recoveries of 5 elements were between 91% and 112% while the precisions were less than 2%. The determination limit of lead, cadmium, copper, arsenic and mercury were 0.28, 0.014, 0.49, 0.19, 0.061 microg x L(-1), respectively. The proposed method was simple, sensitive, accurate and reliable, and could be used widely.

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