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Zhongguo Zhong Yao Za Zhi. 2008 Dec;33(23):2727-32.

[Progress of pharmacological research on icariin].

[Article in Chinese]

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Department of Integrated Chinese and Western Medicine, First Hospital, Peking University, Beijing 100034, China.


Icariin (ICA), as one of the flavones compounds, possess strong pharmacological effects. With wide body distribution, it even could pass through blood-brain barrier into brain tissues. When intaken as a pure compound, distribution of ICA in body was accord with open type of two compartment model. If it is one ingredient of a complex prescription, other component of these could promote the absorption and distribution of ICA. After metabolism, the main component left was its aglycone. A lot of research about ICA based on immunology, phymatology, genesiology and endocrinology sustained it was a valuable compounds. Recently more research about ICA concentrated their interesting to its mysterious effect on bone tissues, cardiovascular system and especially nervous systems.

[Indexed for MEDLINE]

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