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J Biomed Opt. 2009 Jan-Feb;14(1):014017. doi: 10.1117/1.3076198.

Gradient-index lens rod based probe for office-based optical coherence tomography of the human larynx.

Author information

1
University of California, Irvine, Department of Biomedical Engineering, Irvine, California 92697, USA.

Abstract

Optical coherence tomography (OCT) is an evolving noninvasive imaging modality that has been used to image the human larynx during surgical endoscopy. The design of a long gradient-index lens-based probe capable of capturing images of the human larynx by use of spectral domain OCT during a typical office-based laryngoscopy examination is presented. An optical-ballast-based 4f optical relay system is proposed to realize variable working distance with a constant optical delay. In-vivo OCT imaging of the human larynx is demonstrated. Office-based OCT is a promising imaging modality for early laryngeal cancer diagnosis.

PMID:
19256705
PMCID:
PMC2862680
DOI:
10.1117/1.3076198
[Indexed for MEDLINE]
Free PMC Article

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