Format

Send to

Choose Destination
Cell Metab. 2009 Mar;9(3):215-6. doi: 10.1016/j.cmet.2009.02.001.

A sweet path to insulin resistance through PGC-1beta.

Author information

1
Life Sciences Institute and Department of Cell & Developmental Biology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA.

Abstract

Fructose is a highly lipogenic dietary nutrient that has been implicated in the pathogenesis of hyperlipidemia and insulin resistance. In this issue, Nagai et al. (2009) provide in vivo evidence that pinpoints transcriptional coactivator PGC-1beta as a key factor in mediating the metabolic response to fructose intake.

PMID:
19254566
DOI:
10.1016/j.cmet.2009.02.001
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center