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Diabetes Res Clin Pract. 2009 May;84(2):e24-6. doi: 10.1016/j.diabres.2009.02.009. Epub 2009 Feb 28.

Higher dose requirements with insulin detemir in type 2 diabetes--three cases and a review of the literature.

Author information

1
Department of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands. s.g.swinnen@amc.uva.nl

Abstract

We report on three type 2 diabetic patients whose daily basal insulin dose requirements were substantially reduced after switching from insulin detemir to insulin glargine. Meta-analysis of three randomised trials of basal insulin initiation confirmed this increased insulin detemir dose requirement in type 2 patients. Potential explanations are discussed.

PMID:
19251336
DOI:
10.1016/j.diabres.2009.02.009
[Indexed for MEDLINE]

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