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Clin Biochem. 2009 Jun;42(9):907-10. doi: 10.1016/j.clinbiochem.2009.02.010. Epub 2009 Feb 26.

Stability of analytes related to clinical chemistry and bone metabolism in blood specimens after delayed processing.

Author information

1
Universities Space Research Association, Houston, TX, USA. sara.zwart-1@nasa.gov

Abstract

OBJECTIVES:

We investigated the stability of 36 analytes related to clinical chemistry in a controlled storage study.

DESIGN AND METHODS:

Blood was collected from 11 subjects and was maintained for 45 min, 2.5 h, 5 h, or 24 h after phlebotomy before centrifugation.

RESULTS:

Statistically significant changes were observed only for parathyroid hormone, osteocalcin, zinc, pyridoxal 5'-phosphate, and homocysteine.

CONCLUSIONS:

These studies indicate that many analytes in clinical chemistry are stable for 24 h before centrifugation.

[Indexed for MEDLINE]

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