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Semin Fetal Neonatal Med. 2009 Apr;14(2):111-8. doi: 10.1016/j.siny.2008.11.007.

Offspring of diabetic pregnancy: short-term outcomes.

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1
School of Reproductive and Developmental Medicine, University of Liverpool, and Liverpool Women's Hospital, Crown Street, Liverpool L8 7SS, UK. a.m.weindling@liv.ac.uk

Abstract

In spite of clinicians apparently appreciating the risks of maternal diabetes to the baby, babies of mothers with diabetes are still at increased risk compared to those of non-diabetic women. The rate of prematurity in infants of diabetic mothers is five times that of the general population. Women with pre-gestational diabetes give birth to larger babies. In a recent study, half were above the 90th centile for weight. The postnatal management of these babies continues to give cause for concern. In a recent UK study, over half of all infants of diabetic mothers were admitted to a neonatal unit. One-third of these were at term. This admission rate is three times the UK average and examination of cases showed that two-thirds of admissions were unnecessary. It is likely that a high maternal blood glucose concentration is the most important factor causing this increased risk. Babies of women with type 1 and type 2 DM have similar complication rates. Tighter preconceptional glycaemic control as well as during the pregnancy is likely to be important in improving outcome for the babies of diabetic mothers.

PMID:
19249005
DOI:
10.1016/j.siny.2008.11.007
[Indexed for MEDLINE]

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