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Psychiatr Clin North Am. 2009 Mar;32(1):15-37. doi: 10.1016/j.psc.2008.12.001.

Psychiatric phenotypes associated with neurogenetic disorders.

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1
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305-5719, USA. carlf@stanford.edu

Abstract

Advances in understanding the human genome and clinical application have led to identification of genetically based disorders that have distinctive behavioral phenotypes and risk for serious psychiatric disorders. Some patients have unrecognized genetic disorders presenting as psychiatric symptoms. Practitioners must be knowledgeable about the association between symptoms and underlying genetic bases. Treatment of neurogenetic disorders includes providing information about causes and prognoses. Patients are served best if they remain long term with a multidisciplinary team of providers who recognize the realities of a lifetime course, the high risk for symptom recurrence, and the need for providing information and support to families and coordinating medical and psychiatric care.

PMID:
19248914
DOI:
10.1016/j.psc.2008.12.001
[Indexed for MEDLINE]
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