Send to

Choose Destination
Expert Opin Drug Deliv. 2009 Feb;6(2):197-208. doi: 10.1517/17425240802708978 .

Multifunctional coprocessed excipients for improved tabletting performance.

Author information

National Institute of Pharmaceutical Education and Research (NIPER)-Ahmedabad, C/o. B.V. Patel Pharmaceutical Education and Research Development Centre, S.G. Highway, Thaltej, Ahmedabad-380054, India.


With the advancement of tablet manufacturing process, the demand of excipients with improved functionalities, mainly in terms of flow and compression properties, has increased. Coprocessed excipients are a mixture of two or more existing excipients at subparticle level, offer substantial benefits of the incorporated excipients and minimize their drawbacks. These multipurpose excipients have dramatically reduced the number of incorporating excipients in the tablet. The present review discusses the potential advantages of coprocessing and coprocessed excipients, material characteristics required for coprocessing, methods of coprocessing and various coprocessed excipients for direct compression available in the market.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Taylor & Francis
Loading ...
Support Center