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J Psychosom Res. 2009 Mar;66(3):221-5. doi: 10.1016/j.jpsychores.2008.09.014. Epub 2008 Dec 17.

Depressive symptoms in relation to physical functioning in pulmonary hypertension.

Author information

1
Department of Psychiatry, Sir Mortimer B. Davis - Jewish General Hospital, Montreal, Quebec, Canada H3T 1E2. karl.looper@mcgill.ca

Abstract

OBJECTIVE:

To investigate the association between depressive symptoms and physical functioning in pulmonary hypertension (PH) patients.

METHODS:

Fifty-two patients diagnosed with precapillary or postcapillary PH completed self-report questionnaires of depressive symptoms and physical functioning. Cardiac catheterization reports of patients were reviewed for hemodynamic variables.

RESULTS:

Physical functioning was significantly associated with depressive symptoms on bivariate analysis. On multivariate analysis, after controlling for demographic and hemodynamic variables, depressive symptoms accounted for 9% of variance in physical functioning.

CONCLUSION:

The association of depressive symptoms with decreased physical functioning in PH patients indicates the need for longitudinal research regarding the possible effect of depression on disease outcomes in this population.

[Indexed for MEDLINE]

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