Abstract
A 49-year-old woman with high fever and diffuse swelling of the right cheek was referred to our hospital. Computed tomography showed right orbital tumor with massive involvement. Histopathologic examination of the biopsied right orbital tumor demonstrated extranodal NK/T-cell lymphoma, nasal-type. She was treated with six courses of chemotherapy consisting of etoposide and dexamethasone with 50 Gy of concurrent involved-field radiotherapy. Facial swelling and liver dysfunction improved immediately, and after five courses of chemotherapy, she achieved partial remission without any severe adverse events. L-asparaginase was administered in the final course of chemotherapy. There is no evidence of recurrence 56 months after diagnosis.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Asparaginase / administration & dosage
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Combined Modality Therapy
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Dexamethasone / administration & dosage
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Etoposide / administration & dosage
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Female
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Humans
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Liver Diseases / complications*
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Lymphoma, Extranodal NK-T-Cell / complications
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Lymphoma, Extranodal NK-T-Cell / drug therapy*
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Lymphoma, Extranodal NK-T-Cell / radiotherapy*
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Middle Aged
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Neoplasm Invasiveness
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Nose Neoplasms / complications
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Nose Neoplasms / drug therapy*
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Nose Neoplasms / pathology
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Nose Neoplasms / radiotherapy*
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Orbital Neoplasms / complications
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Orbital Neoplasms / drug therapy*
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Orbital Neoplasms / pathology
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Orbital Neoplasms / radiotherapy*
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Radiotherapy Dosage
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Remission Induction
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Time Factors
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Treatment Outcome
Substances
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Etoposide
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Dexamethasone
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Asparaginase