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Dermatology. 2009;218(4):327-33. doi: 10.1159/000203649. Epub 2009 Feb 18.

Tolerance of oat-based topical products in cereal-sensitized adults with atopic dermatitis.

Author information

1
Unité de Recherche Clinique en Immunologie, Centre Hospitalier Lyon Sud, UFR Lyon-Sud, Université Lyon 1, Pierre Bénite, France.

Abstract

BACKGROUND:

Few data suggest oat-based cosmetics may cause allergic reactions in atopic subjects, especially when sensitized to cereals.

OBJECTIVES:

To evaluate the risk of immediate and delayed allergic reactions to repeated and maximized applications (RMA) of oat-containing cosmetics and oat extracts and their tolerance in cereal-sensitized atopic adults.

METHODS:

Open-label pilot study in 12 cereal-sensitized atopic adults over 45 days. Open tests and RMA were performed with Rhealba oat-containing cosmetics at day 0 (D0) and D10, and from D10 to D31. Patch and prick tests were performed at D7 and D42 with wheat and Rhealba oat extracts and the study cream.

RESULTS:

The RMA of oat-based cosmetics in cereal-sensitized atopic adults did not induce any immediate or delayed allergic reaction and was well tolerated. No immediate or delayed positive skin test to oat extracts was observed.

CONCLUSION:

Sensitization to cereals does not increase the risk of allergic reactions to oat-containing cosmetics.

PMID:
19223682
DOI:
10.1159/000203649
[Indexed for MEDLINE]

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