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Ann Chir Plast Esthet. 2009 Dec;54(6):540-4. doi: 10.1016/j.anplas.2008.10.008. Epub 2009 Feb 14.

[Merkel cell carcinoma: study of 24 cases and review of the literature].

[Article in French]

Author information

1
Service de chirurgie plastique reconstructrice et esthétique, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France. drlouafi@yahoo.fr

Abstract

Merkel cell carcinoma is a cutaneous-neuroendocrine tumor, which may be difficult to diagnose and to treat.

OBJECTIVE:

The objective of this study was to analyse the treatment and the recurrences of Merkel cell carcinoma.

PATIENTS AND METHODS:

A retrospective study was performed on the patients operated of a Merkel cell carcinoma between 1994 and 2004. Clinical data of the patients and the tumor, treatment (surgery and radiotherapy) and recurrences were entered in a database.

RESULTS:

Twenty-four patients were operated (8 men and 16 women). The mean age at diagnosis was 71.5 years. The average follow-up was 30.8 months. The treatment was a large surgical removal of the tumor with immediate closure, systematically followed by radiotherapy. There were five recurrences and no death.

CONCLUSION:

Merkel cell carcinoma is an aggressive tumor. Immediate closure after large surgical removal allows radiotherapy.

PMID:
19223109
DOI:
10.1016/j.anplas.2008.10.008
[Indexed for MEDLINE]
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