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Med J Aust. 2009 Feb 16;190(4):176-9.

Prevalence of metabolic syndrome among Australians with severe mental illness.

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1
Mental Health, Bentley Health Service, Perth, WA, Australia. Alexander.John@health.wa.gov.au

Abstract

OBJECTIVE:

To assess the prevalence of metabolic syndrome and its association with sociodemographic, clinical and lifestyle variables among Australian patients with a variety of psychiatric disorders.

DESIGN AND SETTING:

Cross-sectional study of patients attending a public mental health service in Western Australia between July 2005 and September 2006.

PARTICIPANTS:

Patients who were aged 18-65 years; diagnosed with schizophrenia, schizoaffective disorder, bipolar disorder, major depressive disorder with psychotic symptoms, drug-induced psychosis or borderline personality disorder; and currently taking at least one antipsychotic drug for a minimum of 2 weeks.

MAIN OUTCOME MEASURES:

Prevalence of metabolic syndrome diagnosed with International Diabetes Federation criteria; fasting blood glucose and lipid levels; sociodemographic and lifestyle characteristics.

RESULTS:

Of 219 patients invited to participate, 203 agreed and had complete data. Prevalence of metabolic syndrome was 54% overall, and highest among patients with bipolar disorder or schizoaffective disorder (both 67%), followed by schizophrenia (51%). Sociodemographic variables, including age and ethnic background, were not significantly associated with metabolic syndrome, but a strong association was seen with mean body mass index. Other cardiovascular risk factors, such as smoking and substance misuse, were common among participants.

CONCLUSIONS:

Prevalence of metabolic syndrome in this population was almost double that in the general Australian population, and patients with schizophrenia had a prevalence among the highest in the developed world. Prevalence was also high in patients with a variety of other psychiatric disorders.

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PMID:
19220180
[Indexed for MEDLINE]
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