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Kidney Int. 2009 Mar;75(5):455-7. doi: 10.1038/ki.2008.653.

Flying podocytes.

Author information

1
Renal Division, University Hospital Freiburg, Freiburg, Germany.

Abstract

Recent insights have defined the central role of podocytes both in rare genetic diseases and as a general determinant of the progression of human glomerular diseases. In a recent issue of Nature, Weavers et al. described a podocyte-like cell type in Drosophila, the nephrocyte, that closely resembles mammalian podocytes, including the nephrin-based slit diaphragm. This novel podocyte system might open new avenues toward the understanding of podocyte biology and pathophysiology.

PMID:
19219000
DOI:
10.1038/ki.2008.653
[Indexed for MEDLINE]
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