Format

Send to

Choose Destination
See comment in PubMed Commons below
Dev Cell. 2009 Feb;16(2):209-21. doi: 10.1016/j.devcel.2009.01.004.

The control of vascular integrity by endothelial cell junctions: molecular basis and pathological implications.

Author information

1
IFOM, The FIRC Institute of Molecular Oncology, Milan, Italy. elisabetta.dejana@ifom-ieo-campus.it

Abstract

Human pathologies such as vascular malformations, hemorrhagic stroke, and edema have been associated with defects in the organization of endothelial cell junctions. Understanding the molecular basis of these diseases requires different integrated approaches which include basic cell biology, clinical studies, and studies in animal models such as mice and zebrafish. In this review we discuss recent findings derived from these approaches and their possible integration in a common picture.

PMID:
19217423
DOI:
10.1016/j.devcel.2009.01.004
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center