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Childs Nerv Syst. 2009 Oct;25(10):1275-82. doi: 10.1007/s00381-009-0809-7. Epub 2009 Feb 11.

New chemotherapy strategies and biological agents in the treatment of childhood ependymoma.

Author information

1
Division of Neuro Oncology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Mailstop 260, Memphis, TN 38105, USA. karen.wright@stjude.org

Abstract

INTRODUCTION:

With the limited role of current treatment regimens and potential associated side effects of radiation in young children with ependymoma, considerable effort is being focused on new chemotherapeutic strategies and biologic agents.

DISCUSSION AND CONCLUSION:

Identification of those molecular changes underlying the development of ependymoma may, in time, lead to the development of not only novel therapeutic agents, but also specific patient-tailored therapies directed against known cell-signaling pathways.

PMID:
19212772
PMCID:
PMC2738756
DOI:
10.1007/s00381-009-0809-7
[Indexed for MEDLINE]
Free PMC Article

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