Format

Send to

Choose Destination
Eur J Dent. 2007 Jan;1(1):21-4.

Fluoride levels of human plasma and breast milk.

Author information

1
Assistant Professor, Selçuk University, Faculty of Dentistry, Department of Pedodontics.

Abstract

OBJECTIVES:

The aim of this study was to determine the fluoride levels in breast milk and plasma of lactating mothers who regularly consumed drinking water with low levels of fluoride.

METHODS:

One hundred twenty five healthy mothers aged between 20-30 years old who had given birth within 5-7 days were included in the study. Besides being otherwise healthy, the primary selection criteria stipulated the absence of fluoride supplement consumption one month before delivery. Approximately 5 ml breast milk and 5 ml blood samples were obtained from each participating mother at a hospital setting, where the mothers were scheduled for a regular hospital diet. The blood samples were centrifuged in fluoride-free heparinized polyethylene tubes and stored at -18 degrees C until measurements were made. Breast milk samples were directly refrigerated as with blood samples until measurements. The fluoride concentrations of milk and blood samples were assessed using an ion-selective fluoride electrode combined with an ion analyzer.

RESULTS:

The fluoride levels of the plasma and breast milk samples were measured as 0.017+/-0.011 ppm and 0.006+/-0.002 ppm, respectively. The fluoride concentration of plasma was significantly higher than that of breast milk (P<.01). Correlation analysis revealed a significant relation between the groups (P<.01).

CONCLUSION:

A limited level of fluoride transmission from plasma to breast milk was detected. Nevertheless, a significant correlation between the fluoride concentrations of breast milk and plasma was evident.

KEYWORDS:

Breast milk; Fluoride; Plasma

PMID:
19212493
PMCID:
PMC2612944

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center