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J Autism Dev Disord. 2009 Jun;39(6):897-909. doi: 10.1007/s10803-009-0692-9. Epub 2009 Feb 10.

Comparative analysis of three screening instruments for autism spectrum disorder in toddlers at high risk.

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Karakter Child and Adolescent Psychiatry University Center, Reinier Postlaan 12, Nijmegen 6525 GC, The Netherlands.


Several instruments have been developed to screen for autism spectrum disorders (ASD) in high-risk populations. However, few studies compare different instruments in one sample. Data were gathered from the Early Screening of Autistic Traits Questionnaire, Social Communication Questionnaire, Communication and Symbolic Behavior Scales-Developmental Profile, Infant-Toddler Checklist and key items of the Checklist for Autism in Toddlers in 238 children (mean age = 29.6 months, SD = 6.4) at risk for ASD. Discriminative properties are compared in the whole sample and in two age groups separately (8-24 months and 25-44 months). No instrument or individual item shows satisfying power in discriminating ASD from non-ASD, but pros and cons of instruments and items are discussed and directions for future research are proposed.

[Indexed for MEDLINE]

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