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Conscious Cogn. 2009 Jun;18(2):449-57. doi: 10.1016/j.concog.2008.12.009. Epub 2009 Feb 6.

Neural functional organization of hallucinations in schizophrenia: multisensory dissolution of pathological emergence in consciousness.

Author information

1
Laboratoire de Neurosciences Fonctionnelles et Pathologies, CNRS UMR-8160, Hôpital Roger Salengro, Université Lille Nord de France, Centre Hospitalier Universitaire de Lille, 59037 Lille cedex, France. r-jardri@chru-lille.fr

Abstract

Although complex hallucinations are extremely vivid, painful symptoms in schizophrenia, little is known about the underlying mechanisms of multisensory integration in such a phenomenon. We investigated the neural basis of these altered states of consciousness in a patient with schizophrenia, by combining state of the art neuroscientific exploratory methods like functional MRI, diffusion tensor imaging, cortical thickness analysis, electrical source reconstruction and trans-cranial magnetic stimulation. The results shed light on the functional architecture of the hallucinatory processes, in which unimodal information from different modalities is strongly functionally connected to higher-order integrative areas.

PMID:
19201210
DOI:
10.1016/j.concog.2008.12.009
[Indexed for MEDLINE]

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