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Arch Pathol Lab Med. 2009 Feb;133(2):289-94. doi: 10.1043/1543-2165-133.2.289.

The spectrum of eosinophilic cystitis in males: case series and literature review.

Author information

1
Division of Anatomic Pathology, Children's and Women's Health Centre of British Columbia, Vancouver, BC, Canada.

Abstract

CONTEXT:

Eosinophilic cystitis (EC) is an inflammatory condition of the bladder that has been linked to food allergens, infectious agents, drugs, and other genitourinary conditions. Like interstitial cystitis, EC has a strong female predominance. It is characterized by an intense eosinophilic infiltrate in the acute phase and fibrosis in the chronic phase.

OBJECTIVES:

To document and focus on specific features of EC in males and highlight the relationship between clinical and histopathologic findings.

DESIGN:

The bladder biopsies of male patients were reviewed. Eight cases of EC were selected.

RESULTS:

Several known associations were noted as well as unreported features and associations such as Charcot-Leyden crystals, celiac disease, lupus anticoagulant, and additional viral and bacterial agents.

CONCLUSIONS:

Eosinophilic cystitis represents a response to a variety of agents and may often be overlooked. The temporally biphasic morphologic features are the hallmark of this condition. Because clinical and imaging studies are not specific, a high index of clinical suspicion is often crucial to the correct diagnosis and proper management of EC.

PMID:
19195972
DOI:
10.1043/1543-2165-133.2.289
[Indexed for MEDLINE]

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