L-methylfolate: a vitamin for your monoamines

J Clin Psychiatry. 2008 Sep;69(9):1352-3. doi: 10.4088/jcp.v69n0901.

Abstract

Synthesis of the monoamine neurotransmitters serotonin, dopamine, and norepinephrine is regulated by L-methylfolate, a derivate of the vitamin folate.

MeSH terms

  • Antidepressive Agents / therapeutic use
  • Brain / drug effects
  • Brain / physiopathology
  • Depressive Disorder / drug therapy
  • Depressive Disorder / physiopathology
  • Dopamine / biosynthesis*
  • Drug Synergism
  • Humans
  • Norepinephrine / biosynthesis*
  • Serotonin / biosynthesis*
  • Tetrahydrofolates / physiology*
  • Tetrahydrofolates / therapeutic use

Substances

  • Antidepressive Agents
  • Tetrahydrofolates
  • Serotonin
  • 5-methyltetrahydrofolate
  • Dopamine
  • Norepinephrine