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J Gen Psychol. 2009 Jan;136(1):71-89. doi: 10.3200/GENP.136.1.71-90.

Taste-aversion conditioning, but not immunosuppression conditioning, occurs under partial water deprivation.

Author information

1
Universitat de Barcelona, Facultat de Psicologia, Departament de Personalitat, Passeig de la Vall d'Hebron, 171, 08035 Barcelona, Spain. jvidal@ub.edu

Abstract

The authors investigated whether conditioned taste aversion and immunosuppression took place when water was available during conditioning and test protocols. The authors elicited taste-aversion conditioning and immunosuppression in outbred CD1-strain mice by pairing a conditioned stimulus (sucrose or saccharin solution) with an unconditioned stimulus (cyclophosphamide) that causes gastrointestinal upset and is immunosuppressive. The authors introduced a new conditioning protocol: 5 pairings of a saccharin solution with a low-dose injection of cyclophosphamide. Under these conditions, the authors generated conditioned aversion to saccharin but did not generate conditioned decrease of the antibody response. The authors conclude that taste-aversion conditioning, but not immunosuppression conditioning, occurred under partial water deprivation.

PMID:
19192851
DOI:
10.3200/GENP.136.1.71-90
[Indexed for MEDLINE]

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