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Items: 20

1.

Acute exacerbations of asthma: epidemiology, biology and the exacerbation-prone phenotype.

Dougherty RH, Fahy JV.

Clin Exp Allergy. 2009 Feb;39(2):193-202. doi: 10.1111/j.1365-2222.2008.03157.x. Review.

2.

The neutrophilic inflammatory phenotype is associated with systemic inflammation in asthma.

Wood LG, Baines KJ, Fu J, Scott HA, Gibson PG.

Chest. 2012 Jul;142(1):86-93. doi: 10.1378/chest.11-1838.

PMID:
22345378
3.

Consensus document on the overlap phenotype COPD-asthma in COPD.

Soler-Cataluña JJ, Cosío B, Izquierdo JL, López-Campos JL, Marín JM, Agüero R, Baloira A, Carrizo S, Esteban C, Galdiz JB, González MC, Miravitlles M, Monsó E, Montemayor T, Morera J, Ortega F, Peces-Barba G, Puente L, Rodríguez JM, Sala E, Sauleda J, Soriano JB, Viejo JL.

Arch Bronconeumol. 2012 Sep;48(9):331-7. Epub 2012 Feb 15. English, Spanish.

4.

The many paths to asthma: phenotype shaped by innate and adaptive immunity.

Kim HY, DeKruyff RH, Umetsu DT.

Nat Immunol. 2010 Jul;11(7):577-84. doi: 10.1038/ni.1892. Epub 2010 Jun 18. Review.

5.

Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.

Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, Calhoun WJ, Castro M, Chung KF, Clark MP, Dweik RA, Fitzpatrick AM, Gaston B, Hew M, Hussain I, Jarjour NN, Israel E, Levy BD, Murphy JR, Peters SP, Teague WG, Meyers DA, Busse WW, Wenzel SE; National Heart, Lung, Blood Institute's Severe Asthma Research Program.

J Allergy Clin Immunol. 2007 Feb;119(2):405-13.

6.

The obesity phenotype in children with asthma.

Jensen ME, Collins CE, Gibson PG, Wood LG.

Paediatr Respir Rev. 2011 Sep;12(3):152-9. doi: 10.1016/j.prrv.2011.01.009. Epub 2011 Mar 4. Review.

PMID:
21722842
7.

Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype.

Lugogo NL, Hollingsworth JW, Howell DL, Que LG, Francisco D, Church TD, Potts-Kant EN, Ingram JL, Wang Y, Jung SH, Kraft M.

Am J Respir Crit Care Med. 2012 Sep 1;186(5):404-11. doi: 10.1164/rccm.201109-1671OC. Epub 2012 Jul 5. Retraction in: Am J Respir Crit Care Med. 2015 Jul 15;192(2):264.

8.

Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program.

Balzar S, Fajt ML, Comhair SA, Erzurum SC, Bleecker E, Busse WW, Castro M, Gaston B, Israel E, Schwartz LB, Curran-Everett D, Moore CG, Wenzel SE.

Am J Respir Crit Care Med. 2011 Feb 1;183(3):299-309. doi: 10.1164/rccm.201002-0295OC. Epub 2010 Sep 2.

9.

Does obesity produce a distinct asthma phenotype?

Lugogo NL, Kraft M, Dixon AE.

J Appl Physiol (1985). 2010 Mar;108(3):729-34. doi: 10.1152/japplphysiol.00845.2009. Epub 2009 Oct 29. Review.

10.

Obesity-associated severe asthma represents a distinct clinical phenotype: analysis of the British Thoracic Society Difficult Asthma Registry Patient cohort according to BMI.

Gibeon D, Batuwita K, Osmond M, Heaney LG, Brightling CE, Niven R, Mansur A, Chaudhuri R, Bucknall CE, Rowe A, Guo Y, Bhavsar PK, Chung KF, Menzies-Gow A.

Chest. 2013 Feb 1;143(2):406-414. doi: 10.1378/chest.12-0872.

PMID:
23064546
11.

Transcription factors GATA-3 and RORγt are important for determining the phenotype of allergic airway inflammation in a murine model of asthma.

Ano S, Morishima Y, Ishii Y, Yoh K, Yageta Y, Ohtsuka S, Matsuyama M, Kawaguchi M, Takahashi S, Hizawa N.

J Immunol. 2013 Feb 1;190(3):1056-65. doi: 10.4049/jimmunol.1202386. Epub 2013 Jan 4.

12.

The overlap phenotype: the (missing) link between asthma and COPD.

Piras B, Miravitlles M.

Multidiscip Respir Med. 2012 Jun 20;7(1):8. doi: 10.1186/2049-6958-7-8. No abstract available.

13.

Influenza A facilitates sensitization to house dust mite in infant mice leading to an asthma phenotype in adulthood.

Al-Garawi A, Fattouh R, Botelho F, Walker TD, Goncharova S, Moore CL, Mori M, Erjefalt JS, Chu DK, Humbles AA, Kolbeck R, Stampfli MR, O'Byrne PM, Coyle AJ, Jordana M.

Mucosal Immunol. 2011 Nov;4(6):682-94. doi: 10.1038/mi.2011.35. Epub 2011 Aug 31.

PMID:
21881572
14.

Does age impact the obese asthma phenotype? Longitudinal asthma control, airway function, and airflow perception among mild persistent asthmatics.

Lang JE, Hossain J, Dixon AE, Shade D, Wise RA, Peters SP, Lima JJ; American Lung Association-Asthma Clinical Research Centers.

Chest. 2011 Dec;140(6):1524-1533. doi: 10.1378/chest.11-0675. Epub 2011 Jul 28.

PMID:
21799027
15.

Dysfunctional breathing phenotype in adults with asthma - incidence and risk factors.

Agache I, Ciobanu C, Paul G, Rogozea L.

Clin Transl Allergy. 2012 Sep 19;2(1):18. doi: 10.1186/2045-7022-2-18.

16.

Application of the asthma phenotype algorithm from the Severe Asthma Research Program to an urban population.

Patrawalla P, Kazeros A, Rogers L, Shao Y, Liu M, Fernandez-Beros ME, Shang S, Reibman J.

PLoS One. 2012;7(9):e44540. doi: 10.1371/journal.pone.0044540. Epub 2012 Sep 13.

17.

Use of exhaled nitric oxide measurement to identify a reactive, at-risk phenotype among patients with asthma.

Dweik RA, Sorkness RL, Wenzel S, Hammel J, Curran-Everett D, Comhair SA, Bleecker E, Busse W, Calhoun WJ, Castro M, Chung KF, Israel E, Jarjour N, Moore W, Peters S, Teague G, Gaston B, Erzurum SC; National Heart, Lung, and Blood Institute Severe Asthma Research Program.

Am J Respir Crit Care Med. 2010 May 15;181(10):1033-41. doi: 10.1164/rccm.200905-0695OC. Epub 2010 Feb 4.

18.

How to diagnose and phenotype asthma.

Nair P, Dasgupta A, Brightling CE, Chung KF.

Clin Chest Med. 2012 Sep;33(3):445-57. doi: 10.1016/j.ccm.2012.05.003. Epub 2012 Jul 7. Review.

PMID:
22929094
19.

An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype.

Holguin F, Comhair SA, Hazen SL, Powers RW, Khatri SS, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Moore WC, Peters SP, Teague WG, Chung KF, Erzurum SC, Wenzel SE.

Am J Respir Crit Care Med. 2013 Jan 15;187(2):153-9. doi: 10.1164/rccm.201207-1270OC. Epub 2012 Nov 29.

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