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J Dermatol. 1991 Apr;18(4):225-9.

Purpura fulminans secondary to Xanthomonas maltophilia sepsis in an adult with aplastic anemia.

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1
Department of Dermatology, Otaru City General Hospital, Japan.

Abstract

Purpura fulminans is a rare disease characterized by purpura ecchymosis, hypotension, and fever associated with disseminated intravascular coagulation. It often begins as a benign infectious process and subsequently progresses to a severe, catastrophic outcome. It is recognized to originate from congenital or acquired protein C deficiency. We present an unusual case of an adult with Xanthomonas maltophilia sepsis that subsequently developed into purpura fulminans with involvement of the four extremities. We discuss the importance of the protein C system in coagulation homeostasis and its relationship to purpura fulminans.

[Indexed for MEDLINE]

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