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Cancer Cell. 2009 Feb 3;15(2):79-80. doi: 10.1016/j.ccr.2009.01.009.

Inflammation and cancer: IL-6 and STAT3 complete the link.

Author information

1
Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

Abstract

There is growing evidence that tumors are sustained and promoted by inflammatory signals from the surrounding microenvironment. Two papers by Grivennikov et al. and Bollrath et al. in this issue of Cancer Cell demonstrate the importance of the interleukin-6 family of proinflammatory cytokines and their downstream effector STAT3 in colitis-associated colon cancer.

PMID:
19185839
PMCID:
PMC3684978
DOI:
10.1016/j.ccr.2009.01.009
[Indexed for MEDLINE]
Free PMC Article

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