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Child Neuropsychol. 2009 Sep;15(5):471-84. doi: 10.1080/09297040802691120.

Neuropsychological functioning in children with non-syndromic cleft of the lip and/or palate.

Author information

1
The University of Iowa College of Medicine, Psychiatry Research, and University of Iowa Hospitals and Clinics, Otolaryngology, Iowa City, IA 52242, USA. Amy-L-Conrad@uiowa.edu

Abstract

OBJECTIVE:

Evaluate neuropsychological functioning in children with non-syndromic cleft of the lip and/or palate (NSCL/P) through profile variance within type of cleft and comparisons to controls.

METHODS:

Children ages 7 to 17 years participated; 66 had a diagnosis of NSCL/P and 87 were healthy controls. Neuropsychological tests of language, visual-perceptual, executive functioning, and memory skills were administered. Between- and within-group differences were assessed.

RESULTS:

Within cleft types, children with NSCLP had an even profile with equal Verbal and Performance IQ (VIQ and PIQ, respectively). Children with non-syndromic cleft palate only (NSCP) had significantly lower VIQ than PIQ, while children with non-syndromic cleft lip only (NSCL) showed a nonsignificant trend for higher VIQ than PIQ. Overall, subjects with NSCL/P performed lower on measures of expressive language and verbal memory than controls.

CONCLUSIONS:

While deficits in verbal and memory skills for children with NSCL/P remain apparent, there is still uncertainty around the possible influence of cleft type on the pattern of deficits.

PMID:
19184778
PMCID:
PMC3218568
DOI:
10.1080/09297040802691120
[Indexed for MEDLINE]
Free PMC Article

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