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Br J Psychiatry. 2009 Feb;194(2):111-6. doi: 10.1192/bjp.bp.108.052159.

Association of headache with childhood adversity and mental disorder: cross-national study.

Author information

1
Hong Kong Mood Disorders Center, The Chinese University of Hong Kong, Hong Kong.

Abstract

BACKGROUND:

Community studies about the association of headache with both childhood family adversities and depression/anxiety disorders are limited.

AIMS:

To assess the independent and joint associations of childhood family adversities and early-onset depression and anxiety disorders with risks of adult-onset headache.

METHOD:

Data were pooled from cross-sectional community surveys conducted in ten Latin and North American, European and Asian countries (n=18 303) by using standardised instruments. Headache and a range of childhood family adversities were assessed by self-report.

RESULTS:

The number of childhood family adversities was associated with adult-onset headache after adjusting for gender, age, country and early-onset depression/anxiety disorder status (for one adversity, hazard ratio (HR)=1.22-1.6; for two adversities, HR=1.19-1.67; for three or more adversities, HR=1.37-1.95). Early and current onset of depression/anxiety disorders were independently associated (HR=1.42-1.89) with adult-onset headache after controlling for number of childhood family adversities.

CONCLUSIONS:

The findings call for a broad developmental perspective concerning risk factors for development of headache.

PMID:
19182169
PMCID:
PMC2794248
DOI:
10.1192/bjp.bp.108.052159
[Indexed for MEDLINE]
Free PMC Article

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