Format

Send to

Choose Destination
See comment in PubMed Commons below
IUBMB Life. 2009 Mar;61(3):222-8. doi: 10.1002/iub.165.

Directed evolution of enzymes: Library screening strategies.

Author information

1
Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Haren, The Netherlands.

Abstract

Directed evolution has become the preferred engineering approach to generate tailor-made enzymes. The method follows the design guidelines of nature: Darwinian selection of genetic variants. This review discusses the different stages of directed evolution experiments with the focus on developments in screening and selection procedures.

PMID:
19180668
DOI:
10.1002/iub.165
Free full text
PubMed Commons home

PubMed Commons

0 comments

    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Support Center