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Langmuir. 2009 Jan 20;25(2):1060-7. doi: 10.1021/la802953v.

Fast disinfecting antimicrobial surfaces.

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1
Department of Polymer Science & Engineering, University of Massachusetts, Amherst, Massachusetts 01003, USA.

Abstract

Silicon wafers and glass surfaces were functionalized with facially amphiphilic antimicrobial copolymers using the "grafting from" technique. Surface-initiated atom transfer radical polymerization (ATRP) was used to grow poly(butylmethacrylate)-co-poly(Boc-aminoethyl methacrylate) from the surfaces. Upon Boc-deprotection, these surfaces became highly antimicrobial and killed S. aureus and E. coli 100% in less than 5 min. The molecular weight and grafting density of the polymer were controlled by varying the polymerization time and initiator surface density. Antimicrobial studies showed that the killing efficiency of these surfaces was independent of polymer layer thickness or grafting density within the range of surfaces studied.

PMID:
19177651
PMCID:
PMC3748578
DOI:
10.1021/la802953v
[Indexed for MEDLINE]
Free PMC Article
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