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J Am Chem Soc. 2009 Feb 4;131(4):1413-5. doi: 10.1021/ja809666h.

Symmetry controls the face geometry of DNA polyhedra.

Author information

1
Department of Chemistry, Markey Center for Structural Biology and Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, USA.

Abstract

Two complementary strategies have been developed to control the face geometry during the self-assembly of DNA polyhedra from branched DNA nanomotifs (tiles). In these approaches, any two interacting tiles are not equivalent in terms of either sequence or orientation; thus, each face must contain an even number of tiles. As a demonstration, DNA cubes, whose each face contains four tiles, have been assembled through these approaches.

PMID:
19173666
DOI:
10.1021/ja809666h
[Indexed for MEDLINE]

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