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Nat Prod Res. 2009;23(2):138-48. doi: 10.1080/14786410801892078.

New principles from seeds of Nigella sativa.

Author information

1
School of Studies in Chemistry and Biochemistry, Vikram University, Ujjain, India. bkmehta@yahoo.com

Abstract

A new triterpene saponin and known steroidal glucoside were isolated from the alcohol extract, and a new cycloartenol from n-hexane extract of seeds of Nigella sativa L. and were identified as 3-O-[beta-D-xylopyranosyl-(1-->2)-alpha-L-rhamnopyranosyl-(1 --> 2)-beta-D-glucopyranosyl]-11-methoxy-16,23-dihydroxy-28-methylolean-12-enoate (1), stigma-5,22-dien-3-beta-D-glucopyranoside (2) and cycloart-23-methyl-7,20, 22-triene-3beta,25-diol (3), respectively. They were characterised on the basis of spectral analysis and comparison with literature data. The hexane and alcohol extract of the seeds showed antimicrobial activity. The antioxidant activity of hexane extract is also described.

PMID:
19173122
DOI:
10.1080/14786410801892078
[Indexed for MEDLINE]

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